GALP antibody (AA 25-84) (AbBy Fluor® 680)

Catalog No. ABIN5003157

Product Details anti-GALP Antibody (AbBy Fluor® 680)

Target: GALP (Galanin-Like Peptide (GALP))

Binding Specificity: AA 25-84

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALP antibody is conjugated to AbBy Fluor® 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GALP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GALP

Target: GALP (Galanin-Like Peptide (GALP))

Alternative Name: GALP/Alarin (GALP Products)

Synonyms: GALP antibody, galanin like peptide antibody, galanin-like peptide antibody, GALP antibody, ci-galp antibody, Galp antibody

Background:

Synonyms: Alarin, Alarin splice variant, Galanin like peptide, Galanin like peptide precursor protein, GALP precursor protein, GALP_HUMAN.

Background: The galanin family of proteins are key members for inflammatory processes and cell proliferation, and may function as potential biomarkers for colon cancer. Produced in both neuronal and nonneuronal cells in the skin, members of the galanin family include galanin, galanin-message associated peptide, galanin-like peptide and alarin. GALP, also known as galanin-like peptide, is a 116 amino acid secreted protein belonging to the galanin family. Mainly produced in the arcuate nucleus of the hypothalamus (ARC) and the posterior pituitary, GALP is thought to function in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion. GALP binds to the G-protein coupled galanin receptors, including GALR1, GALR2 and GALR3, and may also play a role in energy metabolism, with significant implications towards obesity. GALP exits as two alternatively spliced isoforms.