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LY86 antibody (C-Term)

LY86 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500258
  • Target See all LY86 Antibodies
    LY86 (Lymphocyte Antigen 86 (LY86))
    Binding Specificity
    • 15
    • 9
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 32
    • 20
    • 17
    Human
    Host
    • 43
    • 8
    • 4
    Rabbit
    Clonality
    • 45
    • 10
    Polyclonal
    Conjugate
    • 22
    • 6
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LY86 antibody is un-conjugated
    Application
    • 41
    • 19
    • 13
    • 13
    • 11
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects MD-1 at C-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Peptide affinity chromatography
    Immunogen
    MD-1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human MD-1.
    Isotype
    IgG
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    Discover our top product LY86 Primary Antibody
  • Application Notes
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    LY86 (Lymphocyte Antigen 86 (LY86))
    Alternative Name
    LY86 / MD-1 (LY86 Products)
    Synonyms
    MD-1 antibody, MMD-1 antibody, dJ80N2.1 antibody, MD1 antibody, LY86 antibody, lymphocyte antigen 86 antibody, LY86 antibody, Ly86 antibody
    Background
    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.Synonyms: Lymphocyte antigen 86, MD1
    Gene ID
    9450
    NCBI Accession
    NP_004262
    UniProt
    O95711
    Pathways
    Toll-Like Receptors Cascades
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