MAEL antibody (C-Term)

Catalog No. ABIN500218

Product Details anti-MAEL Antibody

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAEL antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: Maelstrom antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Maelstrom.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for MAEL

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Alternative Name: MAEL (MAEL Products)

Synonyms: CT128 antibody, RP11-102C16.1 antibody, SPATA35 antibody, 4933405K18Rik antibody, AU019877 antibody, RGD1309333 antibody, maelstrom spermatogenic transposon silencer antibody, MAEL antibody, Mael antibody

Background: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.Synonyms: Protein maelstrom homolog

Gene ID: 84944

UniProt: Q96JY0