TXNDC12 antibody (AA 21-120) (AbBy Fluor® 750)
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- Target See all TXNDC12 Antibodies
- TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))
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Binding Specificity
- AA 21-120
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TXNDC12 antibody is conjugated to AbBy Fluor® 750
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ERp19
- Isotype
- IgG
- Top Product
- Discover our top product TXNDC12 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))
- Alternative Name
- ERp19 (TXNDC12 Products)
- Synonyms
- AG1 antibody, AGR1 antibody, ERP16 antibody, ERP18 antibody, ERP19 antibody, PDIA16 antibody, TLP19 antibody, hAG-1 antibody, hTLP19 antibody, 0610040B21Rik antibody, ERp16 antibody, ERp19 antibody, RGD1305960 antibody, thioredoxin domain containing 12 antibody, thioredoxin domain containing 12 (endoplasmic reticulum) antibody, TXNDC12 antibody, Txndc12 antibody
- Background
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Synonyms: AG1, AGR1, anterior gradient homolog 1, endoplasmic reticulum protein ERp19, endoplasmic reticulum resident protein 18, endoplasmic reticulum resident protein 19, endoplasmic reticulum thioredoxin superfamily member, 18 kDa, ER protein 18, ER protein 19, ERP 18, ERP16, ERP19, hAG 1, hAG1, hTLP19, PDIA16, protein disulfide isomerase family A, member 16, thioredoxin domain containing 12 endoplasmic reticulum, Thioredoxin domain-containing protein 12, thioredoxin like protein p19, TLP19, TXNDC12, TXD12_HUMAN.
Background: Endoplasmic reticulum proteins (ERps) are widely expressed proteins and localize to the ER. ERp19, ERp29, ERp46, ERp57 and ERp72 may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases, phospholipases or a combination of these. ERp19, also designated thioredoxin domain-containing protein 12 (TXNDC12), and ERp46, also designated thioredoxin domain containing 5 (TXNDC5), belong to the thioredoxin superfamily and contain a thioredoxin fold with a consensus active-site sequence (CxxC). Both ERp19 and ERp46 are widely expressed ER luminal proteins that are most abundant in the liver and are enriched in purified liver ER vesicles. ERp19 shows significant protein thiol-disulfide oxidase activity in vitro, which is dependent on the presence of both active-site cysteines.
- Gene ID
- 51060
- Pathways
- Cell RedoxHomeostasis
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