ERCC6L antibody (AA 301-400) (AbBy Fluor® 680)
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- Target See all ERCC6L Antibodies
- ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
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Binding Specificity
- AA 301-400
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ERCC6L antibody is conjugated to AbBy Fluor® 680
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ERCC6L
- Isotype
- IgG
- Top Product
- Discover our top product ERCC6L Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
- Alternative Name
- ERCC6L (ERCC6L Products)
- Synonyms
- PICH antibody, RAD26L antibody, BC004701 antibody, D330021P09Rik antibody, RGD1565734 antibody, fc22h03 antibody, si:ch211-278b8.3 antibody, wu:fc22h03 antibody, ERCC excision repair 6 like, spindle assembly checkpoint helicase antibody, excision repair cross-complementing rodent repair deficiency complementation group 6 like antibody, DNA excision repair protein ERCC-6-like antibody, excision repair cross-complementation group 6-like antibody, ERCC6L antibody, Ercc6l antibody, LOC100373376 antibody, LOC100494766 antibody, LOC100552957 antibody, LOC100560751 antibody, LOC100563247 antibody, ercc6l antibody
- Background
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Synonyms: ATP dependent helicase ERCC6 like, DNA excision repair protein ERCC 6 like, ERCC 6L, ERCC6L, Excision repair cross complementing rodent repair deficiency complementation group 6 like, Excision repair protein ERCC6 like, FLJ20105, MGC131695, PICH, Plk1 interacting checkpoint helicase, SNF2/RAD54 family protein, Tumor antigen BJ HCC 15, ERC6L_HUMAN.
Background: ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.
- Gene ID
- 54821
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