EI24 antibody (AA 251-340) (AbBy Fluor® 750)

Catalog No. ABIN5001845

Product Details anti-EI24 Antibody (AbBy Fluor® 750)

Target: EI24 (Etoposide Induced 2.4 (EI24))

Binding Specificity: AA 251-340

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EI24 antibody is conjugated to AbBy Fluor® 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TP53I8/EI24

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EI24

Target: EI24 (Etoposide Induced 2.4 (EI24))

Alternative Name: EI24 (EI24 Products)

Background:

Synonyms: Ei24, EI24_HUMAN, EPG4, Etoposide induced 2.4 mRNA, Etoposide-induced protein 2.4 homolog, p53-induced gene 8 protein, PIG8, TP53I8, Tumor protein p53 inducible protein 8.

Background: This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Gene ID: 9538