DCST1 antibody (AA 265-370) (AbBy Fluor® 750)

Catalog No. ABIN5001075

Product Details anti-DCST1 Antibody (AbBy Fluor® 750)

Target: DCST1 (DC-STAMP Domain Containing 1 (DCST1))

Binding Specificity: AA 265-370

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCST1 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DCST1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DCST1

Target: DCST1 (DC-STAMP Domain Containing 1 (DCST1))

Alternative Name: DCST1 (DCST1 Products)

Synonyms: Dcst1 antibody, RGD1307756 antibody, A330106H01Rik antibody, DC-STAMP domain containing 1 antibody, DCST1 antibody, dcst1 antibody, Sulku_2582 antibody, Dcst1 antibody

Background:

Synonyms: RP11 307C12.10, DC STAMP domain containing 1, FLJ32785, DC-STAMP domain-containing protein 1, DCST1_HUMAN.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gene ID: 149095