DACH1 antibody (AA 301-400) (AbBy Fluor® 680)

Catalog No. ABIN5000973

Product Details anti-DACH1 Antibody (AbBy Fluor® 680)

Target: DACH1 (Dachshund 1 (DACH1))

Binding Specificity: AA 301-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DACH1 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DACH1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DACH1

Target: DACH1 (Dachshund 1 (DACH1))

Alternative Name: DACH1 (DACH1 Products)

Synonyms: DACH antibody, AI182278 antibody, Dac antibody, Dach antibody, E130112M23Rik antibody, dach antibody, dachshund family transcription factor 1 antibody, dachshund 1 (Drosophila) antibody, dachshund family transcription factor 1 S homeolog antibody, dachshund homolog 1 antibody, DACH1 antibody, Dach1 antibody, dach1.S antibody, dach1 antibody, LOC100550020 antibody

Background:

Synonyms: DACH, Dach1, DACH1_HUMAN, dachshund homolog 1 Drosophila, Dachshund homolog 1, Dachsund homolog 1.

Background: DACH1 is similar to the Drosophila melanogaster dachshund gene, which encodes a nuclear factor essential for determining cell fates in the eye, leg, and nervous system of the fly. It is a member of the Ski gene family and is thought to be involved in eye development. Four alternatively spliced transcripts encoding different isoforms have been described for this gene. (from Entrez gene). DACH1 has also been found to inhibit oncogene-mediated breast tumor growth via downregulation of cyclin D1. Expression of DACH1 has been found to inversely correlate with metastasis.

Gene ID: 1602

Pathways: Feeding Behaviour