CTNND2 antibody (AA 951-1050) (AbBy Fluor® 750)
-
- Target See all CTNND2 Antibodies
- CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
-
Binding Specificity
- AA 951-1050
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CTNND2 antibody is conjugated to AbBy Fluor® 750
-
Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human delta 2 Catenin
- Isotype
- IgG
- Top Product
- Discover our top product CTNND2 Primary Antibody
-
-
- Application Notes
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
- Alternative Name
- CTNND2/delta 2 Catenin (CTNND2 Products)
- Synonyms
- CTNND2 antibody, Catnd2 antibody, Nprap antibody, neurojugin antibody, GT24 antibody, NPRAP antibody, ctnnd2 antibody, si:dkey-40c17.4 antibody, catenin delta 2 antibody, delta-catenin antibody, catenin delta-2 antibody, catenin (cadherin associated protein), delta 2 antibody, catenin (cadherin-associated protein), delta 2b antibody, CTNND2 antibody, BACOIKO001_27 antibody, LOC100070792 antibody, Ctnnd2 antibody, ctnnd2b antibody
- Background
-
Synonyms: Catenin cadherin associated protein delta 2, Catenin delta 2, Catenin delta-2, CTND2_HUMAN, CTNND 2, CTNND2, Delta catenin, Delta-catenin, GT 24, GT24, Neural plakophilin related arm repeat protein, Neural plakophilin related armadillo repeat protein, Neural plakophilin-related ARM-repeat protein, Neurojungin, NPRAP
Background: The Alpha-, Beta-, Gamma-, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin also complexes with the tumor suppressor protein APC. Gamma-catenin, also known as plakoglobin, is a protein that binds ?catenin and N-cadherin. Gamma-catenin interacts with presenilin 1 and is expressed in the brain. The gene encoding Gamma-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. In addition, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling.
-