CPNE6 antibody (AbBy Fluor® 750)

Catalog No. ABIN5000400

Product Details anti-CPNE6 Antibody (AbBy Fluor® 750)

Target: CPNE6 (Copine VI (CPNE6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPNE6 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Copine-6

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CPNE6

Target: CPNE6 (Copine VI (CPNE6))

Alternative Name: Copine-6 (CPNE6 Products)

Synonyms: CPNE6 antibody, AU067659 antibody, BB076446 antibody, Copine-6 antibody, copine 6 antibody, copine VI antibody, CPNE6 antibody, Cpne6 antibody

Background:

Synonyms: Copine 6, Copine VI neuronal, Copine VI, Copine-6, Copine6, CopineVI, CPNE 6, Cpne6, CPNE6_HUMAN, N copine, N-copine, Neuronal copine, Neuronal-copine.

Background: Copine 6 is a 557 amino acid member of the copine family of evolutionarily conserved, soluble, calcium-dependent, membrane-binding proteins. Members of the copine family are involved in signal transduction and membrane trafficking. Arabidopsis thaliana mutants lacking copine proteins exhibit reduced cell number and smaller cell size, effects which may be due to a defect in vesicle fusion or transport. Copine 6 contains two N-terminal C2 domains and one C-terminal VWFA (von Willebrand factor A) domain, which is also referred to as the A domain or the core domain. As is characteristic of the copine family, copine 6 functions in membrane trafficking and is capable of binding phospholipids in a calcium-dependent manner. Copine 6 may also play a role in synaptic plasticity.