Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ILP-2 antibody

BIRC8 Reactivity: Human, Rat, Mouse WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500020
  • Target See all ILP-2 (BIRC8) Antibodies
    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
    Reactivity
    Human, Rat, Mouse
    Host
    • 30
    • 2
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ILP-2 antibody is un-conjugated
    Application
    • 13
    • 13
    • 9
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    Human ILP-2 Peptide
    Isotype
    IgG
    Top Product
    Discover our top product BIRC8 Primary Antibody
  • Application Notes
    ELISA. Western Blot: 1 to 2 μg/mL. Human HepG2 or MOLT4 cell lysate can be used as a positivecontrol and a band at approximately 33 kDa can be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
    Alternative Name
    BIRC8 / ILP2 (BIRC8 Products)
    Synonyms
    ILP-2 antibody, ILP2 antibody, hILP2 antibody, baculoviral IAP repeat containing 8 antibody, BIRC8 antibody
    Background
    Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.Synonyms: Baculoviral IAP repeat-containing protein 8, IAP-like protein 2, ILP-2, Inhibitor of apoptosis-like protein 2, Testis-specific inhibitor of apoptosis
    Gene ID
    112401
    NCBI Accession
    NP_203127
    UniProt
    Q96P09
You are here:
Support