CCDC50 antibody (AA 251-306) (AbBy Fluor® 680)

Catalog No. ABIN4999270

Product Details anti-CCDC50 Antibody (AbBy Fluor® 680)

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Binding Specificity: AA 251-306

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC50 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC50

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC50

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Alternative Name: CCDC50 (CCDC50 Products)

Synonyms: ymer antibody, C3orf6 antibody, DFNA44 antibody, YMER antibody, 2610529H08Rik antibody, 5730448P06Rik antibody, AW048328 antibody, AW546090 antibody, D16Bwg1543e antibody, C3orf6h antibody, c3orf6 antibody, coiled-coil domain containing 50 antibody, coiled-coil domain containing 50 L homeolog antibody, CCDC50 antibody, ccdc50.L antibody, ccdc50 antibody, Ccdc50 antibody

Background:

Synonyms: C3orf6, C3orf6 YMER, CCD50_HUMAN, CCDC 50, Ccdc50, Chromosome 3 open reading frame 6, Coiled coil domain containing 50, Coiled coil domain containing protein 50, Coiled-coil domain-containing protein 50, Protein Ymer, Ymer, Ymer protein.

Background: This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].

Gene ID: 152137