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CCDC39 antibody (AbBy Fluor® 680)

CCDC39 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal AbBy Fluor® 680
Catalog No. ABIN4999254
  • Target See all CCDC39 Antibodies
    CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))
    Reactivity
    • 31
    • 22
    • 13
    • 9
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 31
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCDC39 antibody is conjugated to AbBy Fluor® 680
    Application
    • 30
    • 16
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CCDC39
    Isotype
    IgG
    Top Product
    Discover our top product CCDC39 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))
    Alternative Name
    CCDC39 (CCDC39 Products)
    Synonyms
    4921507O14Rik antibody, AI447426 antibody, AI844750 antibody, D3Ertd789e antibody, b2b1304Clo antibody, b2b1735Clo antibody, RGD1306277 antibody, CILD14 antibody, FAP59 antibody, coiled-coil domain containing 39 antibody, flagellar associated protein antibody, Ccdc39 antibody, CCDC39 antibody, ccdc39 antibody, FAP59 antibody
    Background

    Synonyms: CCD39_HUMAN, Ccdc39, Coiled-coil domain-containing protein 39.

    Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

    Gene ID
    339829
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