CAPRIN2 antibody (AA 101-200) (AbBy Fluor® 680)

Catalog No. ABIN4999009

Product Details anti-CAPRIN2 Antibody (AbBy Fluor® 680)

Target: CAPRIN2 (Caprin Family Member 2 (CAPRIN2))

Binding Specificity: AA 101-200

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPRIN2 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CAPRIN2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CAPRIN2

Target: CAPRIN2 (Caprin Family Member 2 (CAPRIN2))

Alternative Name: CAPRIN2 (CAPRIN2 Products)

Synonyms: C1QDC1 antibody, EEG-1 antibody, EEG1 antibody, RNG140 antibody, AA536741 antibody, AV149826 antibody, BC025636 antibody, C1qdc1 antibody, Eeg1 antibody, mKIAA1873 antibody, rng140 antibody, Rng140 antibody, caprin family member 2 antibody, CAPRIN2 antibody, Caprin2 antibody

Background:

Synonyms: C1q domain-containing protein 1, C1QDC1, CAPR2_HUMAN, Caprin family member 2, Caprin-2, caprin2, Cytoplasmic activation/proliferation-associated protein 2, EEG 1, EEG1, Gastric cancer multidrug resistance-associated protein, KIAA1873, Protein EEG-1, RNA granule protein 140, RNG140.

Background: Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic _-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.

Gene ID: 65981

UniProt: Q6IMN6