PTPLA antibody (AbBy Fluor® 750)
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- Target See all PTPLA Antibodies
- PTPLA (Protein Tyrosine Phosphatase-Like (Proline Instead of Catalytic Arginine), Member A (PTPLA))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTPLA antibody is conjugated to AbBy Fluor® 750
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Brd4/CAP
- Isotype
- IgG
- Top Product
- Discover our top product PTPLA Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PTPLA (Protein Tyrosine Phosphatase-Like (Proline Instead of Catalytic Arginine), Member A (PTPLA))
- Alternative Name
- CAP (PTPLA Products)
- Synonyms
- HACD1 antibody, CAP antibody, hacd1 antibody, ptpla antibody, 3-hydroxyacyl-CoA dehydratase 1 antibody, 3-hydroxyacyl-CoA dehydratase 1 L homeolog antibody, Hacd1 antibody, HACD1 antibody, hacd1.L antibody
- Background
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Synonyms: Brd4, BRD4_HUMAN, bromodomain containing protein 4, Bromodomain-containing protein 4, CAP, chromosome associated protein, HUNK1, Protein HUNK1.
Background: Brd4 belongs to the BET family, a group of structurally related proteins containing two bromodomains. Through these two domains, Brd4 associates with mitotic chromosomes and its expression correlates with cell growth. Expression of Brd4 inhibits cell cycle progression from G(1) to S, due to binding to the largest subunit of replication factor C (RFC) to prevent DNA elongation. Altered Brd4 function correlates with poorly differentiated carcinoma, with aggresive phenotype and a highly lethal outcome.
- Gene ID
- 23476
- UniProt
- O60885
- Pathways
- Regulation of long-term Neuronal Synaptic Plasticity
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