CACNA1S antibody (AA 951-1001) (AbBy Fluor® 750)
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- Target See all CACNA1S Antibodies
- CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
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Binding Specificity
- AA 951-1001
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CACNA1S antibody is conjugated to AbBy Fluor® 750
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CACNA1S
- Isotype
- IgG
- Top Product
- Discover our top product CACNA1S Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
- Alternative Name
- CACNA1S (CACNA1S Products)
- Synonyms
- CACNA1S antibody, cav1.1 antibody, ca(v)1.1 antibody, CACNL1A3 antibody, CCHL1A3 antibody, Cav1.1 antibody, HOKPP antibody, HOKPP1 antibody, MHS5 antibody, TTPP1 antibody, hypoPP antibody, AW493108 antibody, Cchl1a3 antibody, fmd antibody, mdg antibody, sj antibody, caV1.1 antibody, calcium voltage-gated channel subunit alpha1 S antibody, calcium channel, voltage-dependent, L type, alpha 1S subunit S homeolog antibody, calcium channel, voltage-dependent, L type, alpha 1S subunit antibody, CACNA1S antibody, cacna1s.S antibody, Cacna1s antibody
- Background
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Synonyms: Voltage-dependent L-type calcium channel subunit alpha-1S, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Voltage-gated calcium channel subunit alpha Cav1.1, CACNA1S, CACH1, CACN1, CACNL1A3
Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.
- Gene ID
- 779
- UniProt
- Q13698
- Pathways
- Skeletal Muscle Fiber Development
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