C6orf70 antibody (AA 151-250) (AbBy Fluor® 680)

Catalog No. ABIN4998647

Product Details anti-C6orf70 Antibody (AbBy Fluor® 680)

Target: C6orf70 (ERMARD) (ER Membrane-Associated RNA Degradation (ERMARD))

Binding Specificity: AA 151-250

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C6orf70 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf70

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C6orf70

Target: C6orf70 (ERMARD) (ER Membrane-Associated RNA Degradation (ERMARD))

Alternative Name: C6orf70 (ERMARD Products)

Synonyms: C6orf70 antibody, dJ266L20.3 antibody, ER membrane associated RNA degradation antibody, ERMARD antibody

Background:

Synonyms: C6orf70, CF070_HUMAN, Chromosome 6 open reading frame 70, dJ266L20.3, FLJ11152, OTTHUMP00000017683, RP1-266L20.6, Transmembrane protein C6orf70.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf70 gene product has been provisionally designated C6orf70 pending further characterization.

Gene ID: 55780