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FNIP2 antibody (C-Term)

FNIP2 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499853
  • Target See all FNIP2 Antibodies
    FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
    Binding Specificity
    • 9
    • 8
    • 7
    • 3
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    This FNIP2 antibody is un-conjugated
    Application
    • 19
    • 15
    • 14
    • 14
    • 5
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to FNIP2.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    FNIP2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human FNIP2.
    Isotype
    IgG
    Top Product
    Discover our top product FNIP2 Primary Antibody
  • Application Notes
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
    Alternative Name
    FNIP2 (FNIP2 Products)
    Synonyms
    LOC797213 antibody, FNIPL antibody, MAPO1 antibody, D630023B12Rik antibody, mKIAA1450 antibody, RGD1562174 antibody, folliculin interacting protein 2 antibody, si:ch211-42i9.8 antibody, FNIP2 antibody, si:ch211-42i9.8 antibody, fnip2 antibody, Fnip2 antibody
    Background
    FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49 % identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship. Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.Synonyms: FNIP1-like protein, FNIPL, Folliculin-interacting protein 2, KIAA1450, MAPO1, O6-methylguanine-induced apoptosis 1 protein
    Gene ID
    57600
    NCBI Accession
    NP_065891
    UniProt
    Q9P278
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