ELOVL6 antibody (N-Term)

Catalog No. ABIN499786

Product Details anti-ELOVL6 Antibody

Target: ELOVL6 (ELOVL Fatty Acid Elongase 6 (ELOVL6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to ELOVL6.

Purification: Affinity Purified

Immunogen: ELOVL6 antibody was raised against a 16 amino acid peptide near the amino terminus of the human ELOVL6.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for ELOVL6

Target: ELOVL6 (ELOVL Fatty Acid Elongase 6 (ELOVL6))

Alternative Name: ELOVL6 (ELOVL6 Products)

Synonyms: FACE antibody, FAE antibody, LCE antibody, C77826 antibody, Lce2 antibody, rELO2 antibody, lce antibody, cb618 antibody, zgc:73089 antibody, elovl6 antibody, ELOVL fatty acid elongase 6 antibody, ELOVL family member 6, elongation of long chain fatty acids (yeast) antibody, elongation of very long chain fatty acids protein 6 antibody, elongation of very long chain fatty acids protein 6-like antibody, ELOVL6 antibody, Elovl6 antibody, elovl6 antibody, Tsp_06132 antibody, LOC108710167 antibody

Background: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.Synonyms: Elongation of very long chain fatty acids protein 6, FACE, Fatty acyl-CoA elongase, LCE, Long-chain fatty-acyl elongase, hELO2

Gene ID: 79071

NCBI Accession: NP_076995

UniProt: Q9H5J4