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BTD antibody (AA 401-500) (AbBy Fluor® 750)

BTD Reactivity: Rat IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 750
Catalog No. ABIN4997678
  • Target See all BTD Antibodies
    BTD (Biotinidase (BTD))
    Binding Specificity
    • 14
    • 5
    • 5
    • 2
    • 1
    • 1
    AA 401-500
    Reactivity
    • 26
    • 17
    • 3
    • 1
    Rat
    Host
    • 34
    • 4
    • 2
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BTD antibody is conjugated to AbBy Fluor® 750
    Application
    • 13
    • 12
    • 12
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Biotinidase
    Isotype
    IgG
    Top Product
    Discover our top product BTD Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    BTD (Biotinidase (BTD))
    Alternative Name
    BTD/Biotinidase (BTD Products)
    Synonyms
    BTD antibody, CG3599 antibody, CT12113 antibody, Dmel\\CG3599 antibody, zgc:153333 antibody, Biotinase antibody, Biotinidase antibody, biotinidase antibody, Btnd antibody, btd antibody, BTD antibody, Btd antibody
    Background

    Synonyms: Biotinase, Biotinidase, Btd, BTD_HUMAN, EC 3.5.1.12.

    Background: Biotin, also known as vitamin B7, is an essential water-soluble vitamin that is a cofactor in glucogenesis and in the metabolism of fatty acids and leucine. Biotinidase is a 523 amino acid enzyme that catalyzes the hydrolysis of biocytin to biotin and lysine. Secreted into extracellular space, biotinidase is expressed in liver, heart, placenta, brain, skeletal muscle, pancreas and kidney. Biotinidase contains one carbon-nitrogen hydrolase domain, which is involved in the reduction of organic nitrogen compounds and ammonia production. Defects in the gene encoding biotinidase are the cause of biotinidase deficiency, which is characterized by skin rash, ataxia, seizures, hearing loss, hypotonia and optic atrophy. These symptoms are due to the individual?s inability to reutilize biotin and can, therefore, typically be treated with the addition of free biotin.

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