TP53BP2 antibody (AA 1090-1128) (AbBy Fluor® 680)
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- Target See all TP53BP2 Antibodies
- TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))
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Binding Specificity
- AA 1090-1128
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TP53BP2 antibody is conjugated to AbBy Fluor® 680
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ASPP2
- Isotype
- IgG
- Top Product
- Discover our top product TP53BP2 Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))
- Alternative Name
- ASPP2/ p53BP2 (TP53BP2 Products)
- Synonyms
- 53BP2 antibody, ASPP2 antibody, BBP antibody, P53BP2 antibody, PPP1R13A antibody, TP53BP2 antibody, AI746547 antibody, Tp53bp2 antibody, X98550 antibody, Trp53bp2 antibody, wu:fa09h08 antibody, wu:fb04e08 antibody, zgc:85720 antibody, tumor protein p53 binding protein 2 antibody, tumor protein p53 binding protein 2 L homeolog antibody, tumor protein p53 binding protein, 2b antibody, transformation related protein 53 binding protein 2 antibody, tumor protein p53 binding protein, 2 antibody, tumor protein p53 binding protein, 2a antibody, TP53BP2 antibody, tp53bp2.L antibody, tp53bp2 antibody, tp53bp2b antibody, Trp53bp2 antibody, Tp53bp2 antibody, tp53bp2a antibody
- Background
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Synonyms: BBP, 53BP2, ASPP2, P53BP2, PPP1R13A, Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, p53-binding protein 2, TP53BP2
Background: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
- Gene ID
- 7159
- UniProt
- Q13625
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