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CUEDC2 antibody (C-Term)

CUEDC2 Reactivity: Human, Mouse, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499688
  • Target See all CUEDC2 Antibodies
    CUEDC2 (CUE Domain Containing 2 (CUEDC2))
    Binding Specificity
    • 15
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 35
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 48
    • 2
    Rabbit
    Clonality
    • 48
    • 2
    Polyclonal
    Conjugate
    • 26
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CUEDC2 antibody is un-conjugated
    Application
    • 37
    • 14
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to CUEDC2.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    CUEDC2 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CUEDC2.
    Isotype
    IgG
    Top Product
    Discover our top product CUEDC2 Primary Antibody
  • Application Notes
    ELISA. Western Blot: CUEDC2 antibody can be used for detection of CUEDC2 at 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    CUEDC2 (CUE Domain Containing 2 (CUEDC2))
    Alternative Name
    CUEDC2 (CUEDC2 Products)
    Synonyms
    cuedc2 antibody, MGC81368 antibody, C10orf66 antibody, bA18I14.5 antibody, 3010002G01Rik antibody, wu:fi42e02 antibody, zgc:92255 antibody, CUE domain containing 2 S homeolog antibody, CUE domain containing 2 antibody, CUE domain containing 2 L homeolog antibody, cuedc2.S antibody, CUEDC2 antibody, cuedc2.L antibody, cuedc2 antibody, Cuedc2 antibody
    Background
    The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to interact with IKK-a and IKK-b and decrease the activation of NF-kB by decreasing the activation of IKK. CUEDC2 antibody will not cross-react with CUEDC1.Synonyms: C10orf66, CUE domain-containing protein 2, HOYS6
    Gene ID
    79004
    NCBI Accession
    NP_076945
    UniProt
    Q9H467
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