CUEDC1 antibody (C-Term)

Catalog No. ABIN499686

Product Details anti-CUEDC1 Antibody

Target: CUEDC1 (CUE Domain Containing 1 (CUEDC1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUEDC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CUEDC1.

Purification: Affinity chromatography purified via peptide column

Immunogen: CUEDC1 antibody was raised against a 16 amino acid peptide near the carbocy terminus of human CUEDC1.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CUEDC1 antibody can be used for detection of CUEDC1 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CUEDC1

Target: CUEDC1 (CUE Domain Containing 1 (CUEDC1))

Alternative Name: CUEDC1 (CUEDC1 Products)

Synonyms: AI841487 antibody, C330016O16Rik antibody, RGD1304861 antibody, CUEDC1 antibody, zgc:153423 antibody, zgc:162271 antibody, CUE domain containing 1 antibody, CUE domain containing 1 L homeolog antibody, CUE domain containing 1a antibody, CUE domain containing 1b antibody, CUEDC1 antibody, Cuedc1 antibody, cuedc1.L antibody, cuedc1 antibody, cuedc1a antibody, cuedc1b antibody

Background: The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker. CUEDC1 antibody will not cross-react with CUEDC2.Synonyms: CUE domain-containing protein 1

Gene ID: 404093

UniProt: Q9NWM3