Aquaporin 7 antibody (AA 251-342) (AbBy Fluor® 680)

Catalog No. ABIN4996763

Product Details anti-Aquaporin 7 Antibody (AbBy Fluor® 680)

Target: Aquaporin 7 (AQP7)

Binding Specificity: AA 251-342

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aquaporin 7 antibody is conjugated to AbBy Fluor® 680

Application: Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AQP7

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Aquaporin 7

Target: Aquaporin 7 (AQP7)

Alternative Name: AQP7 (AQP7 Products)

Synonyms: fj98f09 antibody, wu:fj98f09 antibody, zgc:63700 antibody, aqp7l antibody, aqp9 antibody, aqpap antibody, AQP7 antibody, AQP7L antibody, AQP9 antibody, AQPap antibody, GLYCQTL antibody, SAQP7 antibody, aquaporin 7 antibody, aqp7 antibody, AQP7 antibody, Aqp7 antibody

Background:

Synonyms: AQP9, AQP7L, AQPap, GLYCQTL, Aquaporin-7, AQP-7, Aquaglyceroporin-7, Aquaporin adipose, Aquaporin-7-like, AQP7

Background: Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein "aquaporin". Over the last decade, genes for several members of aquaporin family have been cloned, expressed, and their distribution studied in many tissues. AQP0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 (AQP1, purified from red cells) also called CHIP28 (channel forming integral protein, 28kD, 268aa, gene locus 7p14) has been the foundation of the growing family of aquaporin. The lens specific AQP0 represents up to 80 % of total lens membrane protein. Defects in MIP26 are cause of autosomal dominant cataract. The cataract Fraser mutation (CATFR or Shriveled) is a transposon induced splicing error that substitutes a long terminal repeat sequence for the C terminus of MIP. The lens opacity mutation (LOP) is an amino acid substitution that inhibits targeting of MIP to the cell membrane.

Gene ID: 364

UniProt: O14520