CAZIP antibody (C-Term)

Catalog No. ABIN499583

Product Details anti-CAZIP Antibody

Target: CAZIP (MTUS2) (Microtubule-associated Tumor Suppressor Candidate 2 (MTUS2))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAZIP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: CAZIP antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CAZIP.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CAZIP antibody can be used for detection of CAZIP at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for CAZIP

Target: CAZIP (MTUS2) (Microtubule-associated Tumor Suppressor Candidate 2 (MTUS2))

Alternative Name: KIAA0774 (MTUS2 Products)

Synonyms: KIAA0774 antibody, DKFZp468L0812 antibody, CAZIP antibody, ICIS antibody, TIP150 antibody, 5730592G18Rik antibody, A730013O20Rik antibody, AU067634 antibody, C130038G02Rik antibody, Cazip antibody, Gm763 antibody, mKIAA0774 antibody, microtubule associated tumor suppressor candidate 2 antibody, microtubule associated scaffold protein 2 antibody, MTUS2 antibody, Mtus2 antibody

Background: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.Synonyms: KIAA0774, Microtubule plus-end tracking protein TIP150, TIP150, Tracking protein of 150 kDa

Gene ID: 23281

NCBI Accession: NP_001028774

UniProt: Q5JR59