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CARD10 antibody

CARD10 Reactivity: Human, Mouse WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499533
  • Target See all CARD10 Antibodies
    CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))
    Reactivity
    • 33
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 33
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD10 antibody is un-conjugated
    Application
    • 22
    • 18
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    CARD10 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10.
    Purification
    Immunoaffinity
    Immunogen
    Murine CARD10 / Caspase recuitment domain family 10 / CARMA3 / Bimp1 Peptide
    Isotype
    IgG
    Top Product
    Discover our top product CARD10 Primary Antibody
  • Application Notes
    ELISA. Western BLot: CARD10 antibody can be used for detection of CARD10 at 5 - 10 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))
    Alternative Name
    CARD10 / CARMA3 (CARD10 Products)
    Synonyms
    CARD10 antibody, BIMP1 antibody, CARMA3 antibody, AI449026 antibody, Bimp1 antibody, Carma3 antibody, caspase recruitment domain family, member 10 antibody, caspase recruitment domain family member 10 antibody, Card10 antibody, CARD10 antibody
    Background
    Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10 (1). This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules (2). CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-kappaB (1,3). CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the IkappaK complex (4), demonstrating its importance in the regulation of NF-kappaB transcription factor activation.Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 10
    Gene ID
    29775
    UniProt
    F1BA47
    Pathways
    S100 Proteins
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