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CADPS antibody (N-Term)

CADPS Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499525
  • Target See all CADPS Antibodies
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Binding Specificity
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 13
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 13
    • 1
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 12
    • 1
    • 1
    This CADPS antibody is un-conjugated
    Application
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to CAPS1.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    CAPS1 antibody was raised against a 21 amino acid peptide near the amino terminus of the human CAPS1.
    Isotype
    IgG
    Top Product
    Discover our top product CADPS Primary Antibody
  • Application Notes
    ELISA. Western Blot: CAPS1 antibody can be used for detection of CAPS1 by Western blot at 0.25 -0.5 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Alternative Name
    CADPS (CADPS Products)
    Synonyms
    CADPS1 antibody, CAPS antibody, CAPS1 antibody, Caps antibody, Caps1 antibody, Caps2 antibody, AU067781 antibody, mKIAA1121 antibody, CADPS antibody, cadps antibody, MGC122552 antibody, CAPS-1 antibody, caps antibody, caps1 antibody, si:busm1-1i3.1 antibody, si:busm1-6a2.7 antibody, si:dz6a2.7 antibody, calcium dependent secretion activator antibody, Ca2+-dependent secretion activator antibody, Ca2+-dependent activator protein for secretion b antibody, Ca2+ dependent secretion activator antibody, Ca2+ dependent secretion activator L homeolog antibody, Ca2+-dependent activator protein for secretion a antibody, CADPS antibody, Cadps antibody, cadpsb antibody, cadps antibody, cadps.L antibody, cadpsa antibody
    Background
    CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion. Numerous isoforms of CAPS1 are known to exist. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.Synonyms: CAPS, CAPS-1, CAPS1, Calcium-dependent activator protein for secretion 1, Calcium-dependent secretion activator 1, KIAA1121
    Gene ID
    8618
    NCBI Accession
    NP_899631
    UniProt
    Q9ULU8
    Pathways
    Synaptic Vesicle Exocytosis
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