BICD1 antibody (C-Term)
BICD1
Reactivity: Human, Mouse, Rat
WB, IF, EIA
Host: Rabbit
Polyclonal
unconjugated
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- Target See all BICD1 Antibodies
- BICD1 (Bicaudal D Homolog 1 (BICD1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BICD1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificity
- This antibody reacts to BICD1. This antibody will only recognize the larger isoform.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- BICD1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human BICD1.
- Isotype
- IgG
- Top Product
- Discover our top product BICD1 Primary Antibody
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anti-Bicaudal D Homolog 1 (BICD1) (AA 1-70) antibody
BICD1 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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- Application Notes
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ELISA. Western Blot: BICD1 antibody can be used for detection of BICD1 at 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- Target
- BICD1 (Bicaudal D Homolog 1 (BICD1))
- Alternative Name
- BICD1 (BICD1 Products)
- Background
- BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells. At least two isoforms of BICD1 are known to exist.Synonyms: Bic-D1, Protein bicaudal D homolog 1
- Gene ID
- 636
- NCBI Accession
- NP_001705
- UniProt
- Q96G01
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, Maintenance of Protein Location
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