BCAP29 antibody (Intermediate Domain)

Catalog No. ABIN499411

Product Details anti-BCAP29 Antibody

Target: BCAP29 (B-Cell Receptor-Associated Protein 29 (BCAP29))

Binding Specificity: Intermediate Domain

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAP29 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: BAP29 antibody was raised against a 17 amino acid peptide from near the center of human Bap29 Bap29 antibody is specific for isoform a of Bap29 .

Purification: Affinity chromatography purified via peptide column

Immunogen: Human BAP29 (Intermediate Domain) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: Bap29 antibody can be used for the detection of Bap29 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for BCAP29

Target: BCAP29 (B-Cell Receptor-Associated Protein 29 (BCAP29))

Alternative Name: BCAP29 / BAP29 (BCAP29 Products)

Synonyms: AW208404 antibody, Bap29 antibody, BAP29 antibody, B-cell receptor associated protein 29 antibody, B cell receptor associated protein 29 antibody, B-cell receptor-associated protein 29 antibody, BCAP29 antibody, Bcap29 antibody

Background: Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family (1,2). These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors (3). Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins (3). Bap29 possesses multiple isoforms.Synonyms: B-cell receptor-associated protein 29, BCR-associated protein Bap29

Gene ID: 55973

NCBI Accession: NP_001008405

UniProt: Q9UHQ4