TUBA1A antibody (N-Term)

Catalog No. ABIN499269

Product Details anti-TUBA1A Antibody

Target: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This TUBA1A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Alpha-tubulin.

Purification: Affinity chromatography purified via peptide column

Immunogen: Tubulin antibody was raised against a 16 amino acid peptide near the amino terminus of human Tubulin.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: Tubulin antibody can be used for detection of Tubulin at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

References for anti-TUBA1A antibody (ABIN499269)

Ambadipudi, Georges: "Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1001-1006, (2017) (PubMed).

Schmid, Sailland, Novak, Baumlin, Fregien, Salathe: "Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways." in: FEBS letters, Vol. 591, Issue 21, pp. 3493-3506, (2017) (PubMed).

Target Details for TUBA1A

Target: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Alternative Name: alpha Tubulin / TUBA1A / TUBA3 (Tuba1a Products)

Synonyms: Tuba1 antibody, B-ALPHA-1 antibody, LIS3 antibody, TUBA3 antibody, Tuba-1 antibody, TUBA3D antibody, TUBA3E antibody, wu:fb37a10 antibody, 1t antibody, ALPHA 84C antibody, Alpha-Tubulin84B antibody, BEST:LD32507 antibody, CG1913 antibody, DM1alpha antibody, DTA1 antibody, Dmel\CG1913 antibody, T antibody, TBA1_DROME antibody, Talpha1 antibody, Tub antibody, Tub 84B antibody, Tub1C antibody, Tuba84B antibody, Tubalpha1 antibody, a-tub84B antibody, a1t antibody, aTub84B antibody, alpha-Tub antibody, alpha-Tub84B antibody, alpha-tub antibody, alpha-tub84B antibody, alpha-tubulin antibody, alpha-tubulin 84B antibody, alpha1 antibody, alpha1t antibody, alpha1tub antibody, alpha1tub84B antibody, alpha84B antibody, alphaT antibody, alphaTUB antibody, alphaTUB84B antibody, alphaTub antibody, alphaTub1 antibody, alphaTub84 antibody, alphat-1 antibody, alphatub antibody, alphatub84B antibody, anon-EST:Liang-1.59 antibody, anon-EST:Liang-2.30 antibody, chr3R:2914276..2914416 antibody, clone 1.59 antibody, clone 2.30 antibody, l(3)84Bd antibody, l(3)g3 antibody, ms(3)nc33 antibody, nc33 antibody, tub antibody, tubA84B antibody, tubalpha1 antibody, tubulin antibody, TUBA1A antibody, Tuba1a antibody, Tuba2 antibody, alphatub84 antibody, b-alpha-1 antibody, lis3 antibody, tuba1a antibody, tuba1a-a antibody, tuba1a-b antibody, tuba3 antibody, tubulin, alpha 1A antibody, tubulin alpha 1a antibody, tubulin, alpha 1a antibody, tubulin alpha-1B chain antibody, tubulin alpha-1A chain antibody, tubulin alpha-3 chain-like antibody, alpha-Tubulin at 84B antibody, tubulin alpha 1a L homeolog antibody, Tuba1a antibody, TUBA1A antibody, LOC608147 antibody, LOC100392817 antibody, LOC425049 antibody, tuba1a antibody, alphaTub84B antibody, LOC100051840 antibody, LOC100340483 antibody, LOC100726777 antibody, tuba1a.L antibody

Background: Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots.Synonyms: Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-1A chain, Tubulin alpha-3 chain

Gene ID: 7846

UniProt: Q71U36

Pathways: Microtubule Dynamics, M Phase