HNRNPC antibody (N-Term)

Catalog No. ABIN497942

Product Details anti-HNRNPC Antibody

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Binding Specificity: AA 1-142, N-Term

Reactivity: Human, Rat, Mouse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes hnRNP-C1/C2/HNRNPC (1-152).
Cellular Localization: Nucleus.

Cross-Reactivity (Details): Species reactivity (expected):Mouse (100 %), Rat (100 %), Bovine (100 %) and Rabbit (92 %)Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 142 of hnRNP-C1/C2.

Application Details

Application Notes: Western blotting: 1/500-1/3000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin Sections: 1/100-1/250. Positive Controls: 293T, A431, HeLa, HepG2, Molt-4, Raji.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.79 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C.

Target Details for HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Alternative Name: HnRNP-C1/C2 / HNRNPC (HNRNPC Products)

Synonyms: C1 antibody, C2 antibody, HNRNP antibody, HNRPC antibody, SNRPC antibody, MGC53243 antibody, HNRNPC antibody, bZ1G18.4 antibody, fb57h12 antibody, fi16b11 antibody, wu:fb57h12 antibody, wu:fi16b11 antibody, zgc:55701 antibody, AL022939 antibody, D14Wsu171e antibody, Hnrpc antibody, Hnrpc1 antibody, Hnrpc2 antibody, hnRNPC1 antibody, hnRNPC2 antibody, hnrnp-C antibody, hnRNP C antibody, hnrnp antibody, hnrpc antibody, snrpc antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) S homeolog antibody, heterogeneous nuclear ribonucleoprotein C antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) L homeolog antibody, HNRNPC antibody, hnrnpc.S antibody, hnrnpc antibody, Hnrnpc antibody, hnrnpc.L antibody

Background: HnRNP-C1/C2 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.Synonyms: HNRPC, Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1 / hnRNP C2

Gene ID: 3183, 9606

UniProt: P07910