Keratin 5/8 antibody (AA 353-367)

Catalog No. ABIN4956465

Product Details anti-Keratin 5/8 Antibody

Target: Keratin 5/8 (KRT5/8)

Binding Specificity: AA 353-367

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Keratin 5/8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Cross-Reactivity: Cow (Bovine), Pig (Porcine), Hydra, Human, Amphibian, Mouse (Murine)

Purification: purified

Immunogen: human keratin K8, purified

Clone: C22

Isotype: IgG1

Application Details

Application Notes: Dilution for IHC: ready-to-use

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.91

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Target Details for Keratin 5/8

Target: Keratin 5/8 (KRT5/8)

Alternative Name: Keratin K8/K5 (KRT5/8 Products)

Background: C 22 represents an excellent marker for distinguishing carcinomas from all non-epithelial tumors. The antibody specifically reacts with keratins K5 and K8 present in nearly all epithelia. Polypeptide reacting:Mr 52 500, Mr 58 000 keratins (type II keratins K5 and K8, formerly also designated cytokeratins 5 and 8) of human epithelial cells. Epitope has been mapped to aa 353-367 on alpha helical rod domain