ULK1 antibody

Catalog No. ABIN3029449

Product Details anti-ULK1 Antibody

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULK1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Purified

Immunogen: This ULK1 antibody was produced from rabbits immunized with a human recombinant protein.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ULK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ULK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Alternative Name: ULK1 (ULK1 Products)

Synonyms: ATG1 antibody, ATG1A antibody, UNC51 antibody, Unc51.1 antibody, hATG1 antibody, si:dkey-11o18.7 antibody, ulk1 antibody, ULK1 antibody, AU041434 antibody, mKIAA0722 antibody, zgc:195008 antibody, unc-51 like autophagy activating kinase 1 antibody, unc-51 like kinase 1 antibody, unc-51 like autophagy activating kinase 1a antibody, ULK1 antibody, Ulk1 antibody, ulk1b antibody, ulk1a antibody

Background: ULK1/ATG1 is involved in autophagy. It is required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Phosphorylates ATG13. It is involved in axon growth and plays an essential role in neurite extension of cerebellar granule cells. [UniProt]

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagy