Thrombopoietin antibody (AA 243-273)

Catalog No. ABIN3029127

Product Details anti-Thrombopoietin Antibody

Target: Thrombopoietin (THPO)

Binding Specificity: AA 243-273

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thrombopoietin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogen: A portion of amino acids 243-273 from the human protein was used as the immunogen for this TPO antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TPO antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TPO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Thrombopoietin

Target: Thrombopoietin (THPO)

Abstract: THPO Products

Background: Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. It is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.

UniProt: P40225

Pathways: JAK-STAT Signaling, Hormone Activity