TOR2A antibody (AA 194-221)

Catalog No. ABIN3029188

Product Details anti-TOR2A Antibody

Target: TOR2A (Torsin Family 2, Member A (TOR2A))

Binding Specificity: AA 194-221

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOR2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 194-221 from the human protein was used as the immunogen for this TOR2A antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TOR2A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TOR2A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TOR2A

Target: TOR2A (Torsin Family 2, Member A (TOR2A))

Alternative Name: TOR2A (TOR2A Products)

Synonyms: tor2a antibody, TOR2A antibody, zgc:114110 antibody, TORP1 antibody, Prosalusin antibody, Torsin-2A antibody, torsin family 2 member A antibody, torsin family 2, member A L homeolog antibody, torsin family 2, member A antibody, TOR2A antibody, tor2a.L antibody, tor2a antibody, Tor2a antibody

Background: Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis, it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.

UniProt: Q5JU69