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TEK antibody (AA 758-789)

TEK Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029103
  • Target See all TEK Antibodies
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Binding Specificity
    • 20
    • 19
    • 16
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 758-789
    Reactivity
    • 137
    • 76
    • 53
    • 22
    • 4
    • 3
    Human
    Host
    • 129
    • 18
    • 5
    • 3
    • 2
    Rabbit
    Clonality
    • 135
    • 22
    Polyclonal
    Conjugate
    • 73
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    This TEK antibody is un-conjugated
    Application
    • 77
    • 56
    • 40
    • 40
    • 30
    • 30
    • 13
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity (Details)
    Expected species reactivity: Bovine
    Purification
    Purified
    Immunogen
    A portion of amino acids 758-789 from the human protein was used as the immunogen for this TIE2 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TEK Primary Antibody
  • Application Notes
    Titration of the TIE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the TIE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Alternative Name
    TIE2 (TEK Products)
    Synonyms
    TEK antibody, DKFZp469E064 antibody, AA517024 antibody, Cd202b antibody, Hyk antibody, Tie2 antibody, tie-2 antibody, CD202B antibody, TIE-2 antibody, TIE2 antibody, VMCM antibody, VMCM1 antibody, Tie-2 antibody, tie2 antibody, TEK receptor tyrosine kinase antibody, angiopoietin-1 receptor antibody, TEK tyrosine kinase, endothelial antibody, TEK antibody, LOC100408334 antibody, tek antibody, Tek antibody
    Background
    The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
    UniProt
    Q02763
    Pathways
    RTK Signaling, Growth Factor Binding
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