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TIE1 antibody (AA 12-42)

TIE1 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029410
  • Target See all TIE1 Antibodies
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    Binding Specificity
    • 15
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 12-42
    Reactivity
    • 90
    • 37
    • 33
    • 1
    Human, Mouse
    Host
    • 72
    • 20
    • 1
    Rabbit
    Clonality
    • 73
    • 20
    Polyclonal
    Conjugate
    • 40
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIE1 antibody is un-conjugated
    Application
    • 70
    • 41
    • 16
    • 13
    • 13
    • 9
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Purified
    Immunogen
    A portion of amino acids 12-42 from the human protein was used as the immunogen for this TIE1 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TIE1 Primary Antibody
  • Application Notes
    Titration of the TIE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the TIE1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    Alternative Name
    TIE1 (TIE1 Products)
    Synonyms
    JTK14 antibody, TIE antibody, D430008P04Rik antibody, tie-1 antibody, tyrosine kinase with immunoglobulin like and EGF like domains 1 antibody, tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody, tyrosine-protein kinase receptor Tie-1 antibody, endothelium-specific receptor tyrosine kinase 1 antibody, TIE1 antibody, Tie1 antibody, CpipJ_CPIJ018933 antibody, tie1 antibody
    Background
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
    UniProt
    P35590
    Pathways
    RTK Signaling
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