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tau antibody (AA 677-707)

Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031796
  • Target See all tau Antibodies
    tau (tau Protein)
    Binding Specificity
    • 31
    • 31
    • 30
    • 30
    • 27
    • 27
    • 25
    • 25
    • 24
    • 24
    • 24
    • 23
    • 23
    • 22
    • 17
    • 17
    • 17
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 12
    • 11
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    AA 677-707
    Reactivity
    • 579
    • 542
    • 539
    • 42
    • 28
    • 27
    • 18
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 684
    • 38
    • 3
    • 2
    Rabbit
    Clonality
    • 661
    • 65
    • 1
    Polyclonal
    Conjugate
    • 238
    • 40
    • 31
    • 29
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 22
    • 22
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    This tau antibody is un-conjugated
    Application
    • 570
    • 272
    • 263
    • 213
    • 93
    • 85
    • 67
    • 59
    • 53
    • 37
    • 34
    • 17
    • 12
    • 12
    • 12
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity (Details)
    Expected species reactivity: Mouse, Rat, Bovine
    Purification
    Purified
    Immunogen
    A portion of amino acids 677-707 from the human protein was used as the immunogen for this TAU antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product tau Primary Antibody
  • Application Notes
    Titration of the TAU antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the TAU antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    tau (tau Protein)
    Alternative Name
    tau (tau Products)
    Synonyms
    DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, tau antibody, PHF-tau antibody, microtubule associated protein tau antibody, MAPT antibody
    Background
    TAU/MAPT promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt]
    UniProt
    P10636
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