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SUMO2/3 antibody (AA 53-84)

SUMO2/3 Reactivity: Human WB, IF, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032649
  • Target See all SUMO2/3 products
    SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
    Binding Specificity
    • 16
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 53-84
    Reactivity
    • 48
    • 14
    • 14
    • 1
    • 1
    • 1
    Human
    Host
    • 37
    • 10
    • 1
    Rabbit
    Clonality
    • 29
    • 19
    Polyclonal
    Conjugate
    • 14
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SUMO2/3 antibody is un-conjugated
    Application
    • 41
    • 24
    • 14
    • 14
    • 14
    • 13
    • 9
    • 7
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity (Details)
    Expected species reactivity: Mouse, Rat, Bovine, Pig, Primate, Chicken, Zebrafish, Hamster, Xenopus
    Purification
    Purified
    Immunogen
    A portion of amino acids 53-84 from human SUMO3 was used as the immunogen for this SUMO2/3 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the SUMO2/3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the SUMO2/3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
    Alternative Name
    SUMO2/3 (SUMO2/3 Products)
    Synonyms
    SUMO2 antibody, small ubiquitin-like modifier 2 antibody, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)-like antibody, small ubiquitin-related modifier 2 antibody, SUMO2 antibody, LOC711990 antibody, LOC714892 antibody
    Background
    SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
    UniProt
    P55854
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