SUMO3 antibody (AA 38-64)

Catalog No. ABIN3032652

Product Details anti-SUMO3 Antibody

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Binding Specificity: AA 38-64

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogen: A portion of amino acids 38-64 from the human protein was used as the immunogen for this SUMO-3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SUMO-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SUMO-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SUMO3

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Alternative Name: SUMO-3 (SUMO3 Products)

Background: SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.

UniProt: P55854