SPHK1 antibody (AA 313-343)
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- Target See all SPHK1 Antibodies
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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Binding Specificity
- AA 313-343
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPHK1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- Purification
- Purified
- Immunogen
- A portion of amino acids 313-343 from the human protein was used as the immunogen for this SPHK1 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SPHK1 Primary Antibody
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anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibody
SPHK1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal RB03621 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibodySPHK1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1D6 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30), (N-Term) antibodySPHK1 Reactivity: Human WB Host: Rabbit Polyclonal RB3619 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 Reactivity: Human, Mouse, Rat, Primate WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 148-398) antibodySPHK1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibodySPHK1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 313-343), (C-Term) antibodySPHK1 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB15395 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 59-89), (N-Term) antibodySPHK1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB15394 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 50-384) antibodySPHK1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30) antibodySPHK1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Titration of the SPHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the SPHK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
- Alternative Name
- SPHK1 (SPHK1 Products)
- Synonyms
- CG1747 antibody, Dmel\\CG1747 antibody, SK1 antibody, Sphk1 antibody, SPHK1 antibody, F18E5.160 antibody, F18E5_160 antibody, sphingosine kinase 1 antibody, SPHK antibody, 1110006G24Rik antibody, Sk1 antibody, Spk1 antibody, Sphingosine kinase 1 antibody, sphingosine kinase 1 antibody, sphingosine kinase 1 L homeolog antibody, Sk1 antibody, SPHK1 antibody, sphk1.L antibody, Sphk1 antibody
- Background
- SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.
- UniProt
- Q9NYA1
- Pathways
- VEGF Signaling
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