SP1 antibody (AA 677-707)
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- Target See all SP1 Antibodies
- SP1 (Sp1 Transcription Factor (SP1))
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Binding Specificity
- AA 677-707
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SP1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Rat
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 677-707 from the human protein was used as the immunogen for this SP1 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SP1 Primary Antibody
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anti-Sp1 Transcription Factor (SP1) (pThr453) antibody
SP1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 677-707), (C-Term) antibodySP1 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB17350 unconjugated
anti-Sp1 Transcription Factor (SP1) (C-Term) antibodySP1 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1A5 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 522-618) antibodySP1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4B11 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) antibodySP1 Reactivity: Human WB, IHC, IF, ChIP Host: Rabbit Monoclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (pThr739) antibodySP1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-199) antibodySP1 Reactivity: Human, Mouse WB, ELISA, IF Host: Mouse Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 420-620) antibodySP1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Titration of the SP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the SP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- SP1 (Sp1 Transcription Factor (SP1))
- Alternative Name
- SP1 (SP1 Products)
- Background
- Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. [UniProt]
- UniProt
- P08047
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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