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SP1 antibody

SP1 Reactivity: Human WB, ELISA, IF, FACS Host: Mouse Monoclonal 1326CT463-109-176 unconjugated
Catalog No. ABIN3032703
  • Target See all SP1 Antibodies
    SP1 (Sp1 Transcription Factor (SP1))
    Reactivity
    • 97
    • 67
    • 46
    • 11
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 100
    • 12
    • 3
    Mouse
    Clonality
    • 95
    • 20
    Monoclonal
    Conjugate
    • 70
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SP1 antibody is un-conjugated
    Application
    • 93
    • 48
    • 47
    • 40
    • 21
    • 15
    • 14
    • 14
    • 13
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    Purified
    Immunogen
    This SP1 antibody was produced from a mouse immunized with recombinant Specificity Protein 1.
    Clone
    1326CT463-109-176
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product SP1 Primary Antibody
  • Application Notes
    Titration of the SP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 1:25,Immunofluorescence: 1:25,Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the SP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SP1 (Sp1 Transcription Factor (SP1))
    Alternative Name
    SP1 (SP1 Products)
    Synonyms
    fc18h09 antibody, zgc:85950 antibody, wu:fc18h09 antibody, SP1 antibody, 1110003E12Rik antibody, AA450830 antibody, AI845540 antibody, Sp1-1 antibody, sp1 transcription factor antibody, Sp1 transcription factor antibody, Sp1 transcription factor L homeolog antibody, trans-acting transcription factor 1 antibody, sp1 antibody, SP1 antibody, Sp1 antibody, sp1.L antibody
    Background
    Specificity Protein 1/SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. [UniProt]
    UniProt
    P08047
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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