SLUG antibody (AA 98-129)
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- Target See all SLUG (SNAI2) Antibodies
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
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Binding Specificity
- AA 98-129
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLUG antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity (Details)
- Expected species reactivity: Bovine
- Purification
- Purified
- Immunogen
- A portion of amino acids 98-129 from human SNAI2 was used as the immunogen for this SLUG antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SNAI2 Primary Antibody
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- Application Notes
- Titration of the SLUG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the SLUG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
- Alternative Name
- SLUG (SNAI2) (SNAI2 Products)
- Synonyms
- Slug antibody, Slugh antibody, Snail2 antibody, snail family transcriptional repressor 2 antibody, snail family zinc finger 2 antibody, Snai2 antibody
- Background
- SLUG/SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress < a href=../search_result.php?search_txt=e cadherin>E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects. [Wiki]
- UniProt
- O43623
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