RUNX2 antibody (AA 445-474)
-
- Target See all RUNX2 Antibodies
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
-
Binding Specificity
- AA 445-474
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This RUNX2 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 445-474 from the human protein was used as the immunogen for this RUNX2 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product RUNX2 Primary Antibody
-
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibodyRUNX2 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 242-521) antibodyRUNX2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (N-Term) antibodyRUNX2 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reactivity: Human, Rat WB, IF, IHC (p), EIA Host: Mouse Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (Internal Region) antibodyRUNX2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibodyRUNX2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB15321 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reactivity: Human WB, ELISA, IHC, IF, IHC (p) Host: Mouse Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) antibodyRUNX2 Reactivity: Human WB, IP Host: Rabbit Monoclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reactivity: Human WB, IF, IHC (p), EIA Host: Mouse Monoclonal 1D2 unconjugated
-
- Application Notes
- Titration of the RUNX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the RUNX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- Target
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- Alternative Name
- RUNX2 (RUNX2 Products)
- Background
- RUNX2 is a transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation. [UniProt]
- UniProt
- Q13950
-
