RUVBL2 antibody (AA 400-430)

Catalog No. ABIN3032508

Product Details anti-RUVBL2 Antibody

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Binding Specificity: AA 400-430

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUVBL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): Expected species reactivity: Bovine, Xenopus

Purification: Purified

Immunogen: A portion of amino acids 400-430 from the human protein was used as the immunogen for this Reptin antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Reptin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Reptin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for RUVBL2

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Alternative Name: Reptin (RUVBL2 Products)

Background: This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

UniProt: Q9Y230

Pathways: Telomere Maintenance