RBPMS antibody (AA 166-193)
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- Target See all RBPMS Antibodies
- RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))
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Binding Specificity
- AA 166-193
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RBPMS antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity (Details)
- Expected species reactivity: Mouse
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 166-193 from the human protein was used as the immunogen for this RBPMS antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product RBPMS Primary Antibody
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- Application Notes
- Titration of the RBPMS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the RBPMS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))
- Alternative Name
- RBPMS (RBPMS Products)
- Synonyms
- HERMES antibody, 2010300K22Rik antibody, 2700019M19Rik antibody, AU017537 antibody, hermes antibody, RGD1561067 antibody, si:cabz01079824.1 antibody, RNA binding protein with multiple splicing antibody, RNA binding protein gene with multiple splicing antibody, RNA binding protein with multiple splicing L homeolog antibody, RBPMS antibody, Rbpms antibody, rbpms.L antibody, rbpms antibody
- Background
- Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.
- UniProt
- Q93062
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