PRKD3 antibody (AA 860-890)

Catalog No. ABIN3032381

Product Details anti-PRKD3 Antibody

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Binding Specificity: AA 860-890

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Purified

Immunogen: A portion of amino acids 860-890 from the human protein was used as the immunogen for this PKC nu antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PKC nu antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PKC nu antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PRKD3

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Alternative Name: PKC nu (PRKD3 Products)

Synonyms: EPK2 antibody, PKC-NU antibody, PKD3 antibody, PRKCN antibody, nPKC-NU antibody, PRKD3 antibody, 4930557O20Rik antibody, 5730497N19Rik antibody, Pkcnu antibody, Prkcn antibody, protein kinase D3 antibody, PRKD3 antibody, prkd3 antibody, Prkd3 antibody

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

UniProt: O94806