PHOX2B antibody (AA 104-130)

Catalog No. ABIN3032138

Product Details anti-PHOX2B Antibody

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Binding Specificity: AA 104-130

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity (Details): Expected species reactivity: Human, Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 104-130 from the human protein was used as the immunogen for this PHOX2B antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PHOX2B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PHOX2B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHOX2B (PHOX2B Products)

Background: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq].

UniProt: Q99453