GAB1 antibody (pTyr659)

Catalog No. ABIN3028686

Product Details anti-GAB1 Antibody

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Binding Specificity: pTyr659

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB1 antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Cross-Reactivity (Details): Expected species reactivity: Mouse, Bovine

Purification: Antigen affinity purified

Immunogen: This phospho-Gab1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY659 of human Gab1.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-Gab1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-Gab1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for GAB1

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Alternative Name: GAB1 (GAB1 Products)

Synonyms: AA408973 antibody, AW107238 antibody, growth factor receptor bound protein 2-associated protein 1 antibody, GRB2-associated binding protein 1 antibody, GRB2 associated binding protein 1 antibody, Gab1 antibody, GAB1 antibody

Background: Gab1 is a member of the IRS1-like multisubstrate docking protein family. This protein is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis.

UniProt: Q13480

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals